Case Study: Sensor Performance

Custom Single-Use pH Sensor for Bioreactor Platforms

Supporting Culture Biosciences’ Cloud-Connected Bioprocessing Systems

Challenge

Culture Biosciences develops advanced, cloud-connected bioreactors for upstream bioprocess development, enabling rapid process scaling, characterization, and optimization.

To support their platform, they required a high-performance single-use pH sensor capable of:

  • accurate measurements across a wide pH range
  • minimal signal drift
  • compatibility with gamma sterilization
  • reliable performance after extended dry storage
  • seamless integration into single-use bioreactor systems

Standard sensor solutions could not meet these demanding requirements.

 

Solution

Leveraging our expertise in custom sensor development and industrialization, we engineered a tailored single-use pH sensor designed specifically for their application.

The solution combined:

  • excellent dry storage stability
  • high measurement accuracy and repeatability
  • low drift over time
  • full compatibility with single-use bioprocess systems
  • robust design for demanding production environments

 

Results

The customized sensor is now an integral part of Culture Biosciences’ platform, supporting reliable and scalable upstream bioprocess development.

  • accurate and stable pH measurement
  • seamless integration into disposable bioreactors
  • performance stability after long dry storage
  • trusted use in advanced bioprocess workflows

 

Customer Feedback

C.Edington Headshot“We are very pleased to work with Metroglas to develop a single-use glass pH solution for our bioreactors. We needed an option for pH sensing that could cover a wide range of pH with minimal drift, high accuracy, and gamma compatibility. Their responsiveness, high level of sensor quality, and customization made the integration process very smooth and streamlined.”

– Collin Edington, Principal Engineer at Culture Biosciences 

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