Case Study: Sensor Performance

Custom Single-Use pH Sensor for Bioreactor Platforms

Supporting Culture Biosciences’ Cloud-Connected Bioprocessing Systems

Customer Feedback

C.Edington Headshot“We are very pleased to work with Metroglas to develop a single-use glass pH solution for our bioreactors. We needed an option for pH sensing that could cover a wide range of pH with minimal drift, high accuracy, and gamma compatibility. Their responsiveness, high level of sensor quality, and customization made the integration process very smooth and streamlined.”

– Collin Edington, Principal Engineer at Culture Biosciences 

 

 

Culture Biosciences produces cloud-connected bioreactors for upstream bioprocess development, enabling rapid process scaling, characterization, and optimization.

To support their platform, they required a compact single-use pH sensor that could be integrated into the bioreactor in a space-saving manner without compromising measurement performance.

The sensor had to meet the following requirements:

  • Accurate pH measurements
  • Minimal signal drift
  • Compatibility with gamma sterilization
  • Reliable performance after extended dry storage
  • Shaft diameter of 8 mm
  • Smooth integration into single-use bioreactor systems

Based on these requirements, Metroglas developed a pH sensor designed for single-use applications in rigid-wall single-use bioreactors where installation space is limited.

The sensor is now an integral part of the Culture Biosciences platform, providing reliable pH monitoring. Its stable performance after extended dry storage and dependable operation in production environments help ensure consistent process data and support efficient bioprocess development and scale-up.

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